Check interaction with multiple drugs, vaccines, supplements, alcohol, food and diseases.
Our Drug Interaction Checker helps you identify harmful interactions between prescription drugs, over-the-counter medicines, and supplements. With a simple search, ensure your medications work safely together.
Type the name of your medications (e.g., "ibuprofen" or "amlodipine").
Include vitamins, herbs, or OTC drugs for a full picture.
Click "Check Now" to look up drug interactions instantly.
Understand risks, side effects, and alternatives.
Test combinations of 2+ medications at once.
Verify safety for new prescriptions.
Our database refreshes daily with the latest research.
Use our tool on any device—no app needed.
It occurs when two or more medications interfere with each other’s effects, increasing side effects or reducing effectiveness.
Our tool uses data from FDA-approved sources, peer-reviewed studies, and clinical guidelines.
Yes! Our medication drug interaction checker includes supplements like St. John’s Wort, melatonin, and more.
Whether you’re starting a new prescription interaction checker or managing multiple drugs, our tool empowers you to make safer choices. Bookmark this page for quick access to the #1 drug interaction checker drugs professionals recommend.